Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis
نویسندگان
چکیده
Several authors have confirmed that 27 to 38% of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59% of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.
منابع مشابه
Retraction Note: Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis
[This retracts the article DOI: 10.1186/s13013-015-0043-x.].
متن کاملRelationship between bone density and bone metabolism in adolescent idiopathic scoliosis (AIS)
Methods Using dual–energy X ray absorptiometry and bone metabolism markers (bone formation marker; BAP, bone resorption marker; TRAP5b), the bone mineral density of lumbar and bilateral proximal femurs were studied in 41 AIS patients aged 10 to 20 years old, with a mean of 15.2±5.9 years old. Divided into two groups by levels of bone resorption marker (TRAP5b), BMD, BMI and age of menarche were...
متن کاملEvaluation of Patient Outcome and Satisfaction after Surgical Treatment of Adolescent Idiopathic Scoliosis Using Scoliosis Research Society-30
Background: Adolescent idiopathic scoliosis (AIS) may lead to physical and mental problems. It also can adversely affect patient satisfaction and the quality of life. In this study, we assessed the outcomes and satisfaction rate after surgical treatment of AIS using scoliosis research society-30 questionnaire (SRS-30). Methods: We enrolled 135 patients with AIS undergoing corrective surgery...
متن کاملMorphological and bone strength indices in girls with adolescent idiopathic scoliosis and their correlations with leptin and soluble leptin receptor
Objective Previous studies suggested that leptin has profound effects on bone metabolism and growth. Abnormal leptin and soluble leptin receptor (sOB-R) levels and their correlation patterns with bone mineral density and trabecular bone micro-architecture were recently found to be distinct in girls with adolescent idiopathic scoliosis (AIS). Structural Model Index (SMI) and data derived from Fi...
متن کاملBone metabolism and bone mineral density in adolescent idiopathic scoliosis
Methods Bone mineral density (BMD) of the lumbar spine and bilateral proximal femurs (dual energy x-ray absorptiometry) and bone metabolism markers {bone formation marker: serum bone alkaline phosphatase (BAP); bone resorption marker: serum tartrate-resistant acid phosphatase serum band 5 (TRAP5b)} were measured in 55 consecutive AIS subjects aged 10 to 18 years-old (mean: 15.6+/-1.7). BMD, bod...
متن کامل